Search results for "new-onset diabetes mellitus"
showing 2 items of 2 documents
Statins and new-onset diabetes
2013
Statins are highly efficacious lipid modifying agents that reduce the risk for cardiovascular (CV) events in both primary and secondary prevention settings. However, statins affect molecular mechanisms which adversely impact on insulin sensitivity and β-cell function, thereby increasing risk for new onset diabetes mellitus (NOD). Defining the mechanisms involved is the focus of considerable current investigation. The statins reduce the risk for CV events in normoglycemic patients as well as in those with diabetes mellitus (DM) and their benefits outweigh the risk of inducing NOD. We review the clinical evidence for NOD with statin treatment, as well as the potential mechanisms involved. Our…
Three-year mortality after acute myocardial infarction in patients with different diabetic status
2021
Introduction: The prevalence of diabetes mellitus (DM) in patients with myocardial infarction (MI) is estimated at about 25%. Short and long-term prognoses are worse in DM and hyperglycemia compared with non-diabetics. Objectives: Our aim was to analyze the impact of DM and transient hyperglycemia on in-hospital complications and long-term outcomes in MI patients. Patients and Methods: We evaluated a prospective cohort of 58,394 MI patients in the Polish Registry of Acute Coronary Syndrome in terms of in-hospital complications and 30-day, 12-month, and 36-month outcomes between 2009–2012. Results: Type 1 and 2 DM patients underwent invasive diagnostic and therapeutic procedures less frequen…